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Free Biology Games Online

Explore living systems through play. This collection of free biology games turns real concepts into mechanics: command immune cells against pathogen waves in Immune Rush, sort dividing cells through their checkpoints in Mitosis Manager and match drugs to diseases in Pharma-Fix.

You can edit DNA in CRISPR Snipe, defend your gut microbiome in Microbe Midway, watch allele frequencies drift in Drift King or roll into a cryptobiotic tun in Tardigrade Tun. Every game runs instantly in the browser with no download or sign-up, ready for classrooms, homework and curious minds.

Clockwork Cell

Clockwork Cell

Master the 24-hour molecular clockwork cycle by translating PER and TIM proteins, shuttling dimers into the nucleus to repress transcription and triggering the Cryptochrome dawn flush.

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Pheromone Highway

Pheromone Highway

Guide foraging ant swarms using chemical recruitment trails and alarm repellents to solve emergent shortest paths through stigmergy.

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Tardigrade Tun

Tardigrade Tun

Shift between active swimming and cryptobiotic tun state to withstand lethal solar UV flares, flash freezes, boiling acid and cosmic vacuum.

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Wood Wide Web

Wood Wide Web

Guide mycorrhizal fungal threads through subterranean soil, barter nutrients for glucose with trees and dispatch pest warning signals.

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MicroRNA Patrol

MicroRNA Patrol

Control Argonaute complexes to regulate mRNA translation. Balance cellular homeostasis through exact catalytic cleavage and partial seed dimmer braking.

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FoldCraft

FoldCraft

Snap secondary backbone motifs, trigger hydrophobic core collapse and sculpt catalytic active site pockets.

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Immune Rush

Immune Rush

A fast-paced arcade game about the immune system.

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Microbe Midway

Microbe Midway

A frantic shooter about defending your gut microbiome.

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Tolerance Titans

Tolerance Titans

A tower-defense style game about immune tolerance.

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The Transcriptionist

The Transcriptionist

A typing game where you transcribe DNA to RNA, one base at a time.

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Memory Load

Memory Load

A memory-matching game about how sleep consolidates memories.

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Mitosis Manager

Mitosis Manager

A fast-paced sorting game about the cell cycle and cancer prevention.

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Differentiation Director

Differentiation Director

A puzzle game about differentiating stem cells by matching signal pathways.

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Bone Marrow Madness

Bone Marrow Madness

A fast-paced resource management game about creating blood cells.

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Gene Juggler

Gene Juggler

A fast-paced puzzle game about discovering gene sequences.

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Pharma-Fix

Pharma-Fix

A drag-and-drop game about drug effects and side effects.

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Containment Crew

Containment Crew

A fast-paced reaction game about applying public health interventions to stop outbreaks.

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Chemo Crossroads

Chemo Crossroads

A fast-paced shooter about chemotherapy. Target cancer cells and spare healthy cells.

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Toxin Takedown

Toxin Takedown

A fast-paced game about biomagnification. Catch fish but avoid the concentrated toxins!

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CRISPR Snipe

CRISPR Snipe

A physics-based slingshot game about CRISPR gene editing and chromatin navigation.

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Epigenetic Painter

Epigenetic Painter

A fast-paced chromatin remodeling game. Stamp methyl tags to silence transposons and brush acetyl marks to express genes.

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Phage Hunter

Phage Hunter

A fast-paced physics and docking game about bacteriophages and antibiotic-resistant superbugs.

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Stomata Sprint

Stomata Sprint

A valve balancing reflex game. Pump potassium ions to swell guard cells open for carbon dioxide intake and clamp shut against dry heat waves.

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Hydrothermal Haven

Hydrothermal Haven

A fast-paced deep-sea marine ecology arcade game. Manage a hydrothermal vent ecosystem, channel sulfide plumes and shield tubeworms from volcanic eruptions.

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Gross Anatomy Lab

Gross Anatomy Lab

Master human donor dissection techniques, swap surgical tools to expose thoracic organs and identify vital landmarks without cutting delicate nerves.

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Triage Rush

Triage Rush

A fast-paced clinical diagnosis game where you triage acute symptoms, stabilize fluctuating vitals and deliver targeted treatments before patients crash.

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Patho-Scan

Patho-Scan

Investigate patient blood smears and tissue biopsies, adjust optical focus depth, swipe differential stains and tally cell ratios against time.

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Petriquarium

Petriquarium

Nurture Pichia yeast, Spirulina algae and Streptomyces fermenters, harvest insulin and phycocyanin tokens and defend bioreactors against lytic podoviruses in this microbial arcade game.

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Trophic Frenzy

Trophic Frenzy

Guide microscopic swimmers through pelagic freshwater food webs, graze cyanobacteria as a ciliate, swallow ciliates as a rotifer and evade hydras as daphnia in this science arcade game.

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Epitope Striker

Epitope Striker

Type peptide epitope sequences to synthesize monoclonal antibodies and neutralize invading pathogens before they breach the endothelial barrier.

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Chloroplast Citadel

Chloroplast Citadel

Defend leaf veins against invading aphids, spider mites and caterpillars using thylakoid photon harvesters, guard cell turrets and ABA emergency abscission valves in this botany strategy game.

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Lab Dash

Lab Dash

Dash across the wet lab bench, manage experiment orders, pipette reagents, spin centrifuges and deliver certified test results before researcher patience expires in this laboratory time management game.

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Drift King

Drift King

Steward an island herd of Driftites through pure genetic drift: feed carrying capacity, weather bottleneck storms, seed founder colonies and ride runaway mate fads while allele frequencies lurch by luck alone.

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Spin Echo

Spin Echo

Run a real MRI pulse sequence: fire 90 and 180 degree RF pulses, refocus dephasing proton spins into an echo and encode k-space with gradient coils to diagnose tumor, fat, fluid and edema from their T1 and T2 signatures.

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Peppered Pursuit

Peppered Pursuit

Hunt peppered moths as a hungry flycatcher across generations: soot darkens the forest, lichen restores it and every catch steers the allele frequency bar in this Kettlewell natural selection arcade game.

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Punnett Pen

Punnett Pen

Run a breeding farm under contract: pick parents with hidden genotypes, watch real Punnett squares fill at Mendelian ratios and prove carriers with test crosses before the season drains.

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ATP Avenue

ATP Avenue

Sprint a glucose molecule through glycolysis, lap the Krebs cycle wheel and ride the electron transport chain to the ATP synthase jackpot in this cellular respiration platformer.

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Rhodopsin Relay

Rhodopsin Relay

Pilot a fiber-optic implant inside a living brain: fire blue light to excite relay neurons and yellow light to silence seizures on millisecond timing.

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Sanctuary Tycoon

Sanctuary Tycoon

Rebuild a rundown reserve: fence habitat-matched enclosures, pair founders by genetic distance, dodge poachers and rewild endangered species.

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Acre Algebra

Acre Algebra

Grow crops by balancing N-P-K, soil pH and organic matter while keeping fertilizer runoff out of the creek.

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Explore other subjects

These biology games are free forever and work on school Chromebooks, tablets and desktop browsers. Pick a game above or browse the full catalog for more science.

All free science games